Pyrexia was induced with bakers yeast at a dose of 10 mlkg of 30% wv. Antipyretic simple english wikipedia, the free encyclopedia. Antiinflammatory and antipyretic activities of hygrophila. Although the leaves of the plant is used traditionally in the treatment of pyrexia and its antipyretic related activities such as antiinflammatory and analgesic activity were. It also possess antipyretic activity, ethanolic extract significantly reduces fever at higher doses within 3 hrs than petroleum ether extract on brewer. That being said, spinozas views about animal ethics can be. The antipyretic activity of ethanolic extract at a dose of 400 mgkg and 600 mgkg was tested be milk induced pyrexia in rabbits. Pdf antiinflammatory and antipyretic activities of. Be that as it may, spinozas fundamental insight in book one is that. Antipyretic activity of guduchi ghrita formulations in albino. Antipyretic activity of guduchi ghrita formulations in.
Isolation of antifungal and anticancer constituents from this plant was also reported 89. Among philosophers, spinoza is best known for his ethics, a monumental work. Analgesic, antiinflammatory and antipyretic activity of. These are nonsteroidal antiinflammatory drugs nsaids used mainly as analgesics to relieve pain, but which also have antipyretic properties. Rats were fasted overnight with water ad libitum before the experiment. The various plant extract have been used during the ayurvedic times. Medicinal plants with potential antipyretic activity. A natural pge2 inhibitory antipyretic remedy from medicinal plants with minimal toxicity is therefore essential. However, to be clinically useful, more scientific data are needed. Analgesics antipyretics nonsteroidal anti inflammatory. Antipyretic activity of ethanol extracts of echinops echinatus, alhagi maurorum, fagonia cretica, cymbopogon jwarancusa and panicum turgidum form cholistan desert, pakistan was determined. Hygrophila spinosa t ander, belonging to the family acanthaceae, is a promising medicinal plant with great economic potential.
Please note that the above slideshow is automatically created by searching flickr and does. Pendula annonaceae is an evergreen tropical tree well known for its numerous medicinal properties. It is a very common drug and is quite frequently mentioned in most of the samhitas, nighantus, and granthas for its effectiveness in various diseases. Antipyretic activity of medicinal plants of cholistan desert. The plant contains various secondary metabolites as previously reported sen 1996, 1964. Effect of antipyretic activity the results of yeast induced pyrexia test of extract fractions of d. The purpose of this study was to evaluate the extract for antipyretic and analgesic activity, and determine its probable mechanism of action. General information hygrophila auriculata is an erect, stout, branched or unbranched, annual herb growing 150cm or more tall. Antipyretic activity of polyalthia longifolia benth. Antinociceptive, antiinflammatory, and antipyretic.
In the group of rabbits given bukharin, the decline in temperature ranged from 104. To evaluate these properties, fever is induced in rabbits or rats by injection of boiled milk. Acetaminophen or paracetamol, is an analgesic with weak antiinflammatory. Baruch spinoza was a dutch philosopher of portuguese sephardi origin. The results showed that chloroform and alcohol extracts have significant antipyretic activity, but petroleum ether and aqueous extracts failed to lower the raised body temperature in rats. Caesalpinia bonducella fleming caesalpiniaceae plant is well known for its medicinal and therapeutic values in indian ayurveda. Similarly, significant activity p antipyretic medications have other purposes. The subcutaneous injection of boiled milk is known to produce fever in rabbit. Monographical study of biological properties of argemone. Rectal temperature was monitored at 30, 60, and 90 min postadministration of 250 and 500 mgkg of the.
Antipyretic, antiinflammatory and analgesic properties of. Antinociceptive and antipyretic activities of extracts and. Introduction the plants have been used as the natural source of medicine from ancient times. Complete works and millions of other books are available for amazon. Invivo assessment of antipyretic and antiinflammatory.
Schum heine, acanthaceae, has been traditionally used for the treatment of inflammation, pain, urinary infection, edema, gout and as a diuretic. In contrast, the accepted safety of plant derived natural products is inspiring the world. In acetic acid writhing test, the methanol extract, petroleum ether, and. Introduction this bon mot from osler cleverly paints the pall of apprehension felt by those who attend febrile patients at the. Since medicinal plants are also use to treat burns, swelling and malaria, one can expect that they might possess analgesic antiinflammatory and antipyretic activities as well.
For this, several groups of mice n 6 per group weighting 2535 g have been used. Antipyretic activity of methanolic extract of root of tectona grandis linn. The vehicle itself had a moderate antipyretic effect in the initial stages. Hygrophila auriculata is belongs to the genus hygrophila whose identity as a separate genus is still debated. To assess the antiinflammatory, antipyretic and analgesic activities, varied. The crude leaves were extracted with water, ethyl acetate and hexane. Therefore, the antipyretic activity of chloroform and alcoholic extracts of h. Acute toxicity study of eenkc was performed in mice to fix the effective dose. The results showed that chloroform and alcohol extracts have significant antipyretic. Antipyretic activity of some nigerian medicinal plants in rats. Analgesic and antipyretic activities of methanol extract. Investigation of the antiinflammatory, analgesic and. In the present study, we examined the antiinflammatory, antipyretic and analgesic activities of c. Table 1 effect of guduchi ghrita prepared from male and female plants of t cordifolia on yeastinduced pyrexia at various time intervals in albino rats.
Cynodon dactylon, cynodon barberi, antipyretic activity, ethanolic extract, paracetamol 1. Satpathy3 1college of pharmacy, iftm, moradabad 244 001, up, india 2department of pharmaceutical sciences, birla institute of. Male wister rats were fasted overnight with water ad lib before the experiments. Antipyretic and antinociceptive activity of diospyros lotus l. The efficacy of 100mgkg paracetamol was almost equal to that of 400mgkg of the extract at 2 hr after the drug treatment. Antipyretic activity of peperomia pellucidaleaves in rabbit. Satpathy3 1college of pharmacy, iftm, moradabad 244 001, up, india 2department of pharmaceutical sciences, birla institute of technology, mesra, ranchi 835 215, jharkhand, india. May 30, 2011 antipyretic activity of ethanol extracts of echinops echinatus, alhagi maurorum, fagonia cretica, cymbopogon jwarancusa and panicum turgidum form cholistan desert, pakistan was determined. Pyrexia was induced in rabbits by intravenous injection of 10 5 cfu of e. The most common antipyretics in the united states are ibuprofen and aspirin. Petroleum ether, chloroform, alcohol, and aqueous extracts of h. The antipyretic activity observed at a higher dose 400 mgkg was significantly more than that at a lower dose 100 mgkg. Analgesic and antipyretic activities of methanol extract and. Analgesics antipyretics nonsteroidal anti inflammatory drugs.
Paracetamol is similar in analgesic and antipyretic efficacy to acetylsalicylic acid. Ethics, demonstrated in geometrical order usually known as the ethics, is a philosophical treatise written in latin by baruch spinoza. The study was designed to investigate the analgesic activity of methanolic extract of avicennia alba blume fam ily. Moral philosophy internet encyclopedia of philosophy.
Journal of chemical and pharmaceutical research, 2016, 84. From the search, 29 hits were found with different mangrove species reporting one or more of these activities. Antipyretic potential of methanolic stem bark extracts of. The body then works to lower the temperature, which results in a reduction in fever. Antipyretic activity antipyretic activity of drug lyophilized extract was measured by using brewers yeast induced pyrexia in mice. Little is known about spinozas activities in the years immediately following his. Nonopioid analgesics with antiinflammatory activity include salicylates such as. The crude extract strongly ameliorated the induced pyrexia during various assessment. The antipyretic, antiinflammatory and analgesic activity of eenkc was evaluated in brewers yeast induced pyrexia in rats, carrageenaninduced inflammation in rats and aceticacid induced writhing in mice model. A study on antipyretic activity of capparis zeylanica linn. Hygrophila spinosa andres leaves showed significant antibacterial activity when collected between september to october, with less activity seen during other months 129. Antipyretic activity petroleum ether, chloroform, alcohol, and aqueous extracts of astercantha longifolia leaves were evaluated for their antipyretic activity on the basis of their effect on brewers yeastinduced pyrexia in rats. Crude extract ofzizyphus oxyphylla has shown significant activity against carrageenan induced paw edema model at 400 and 200 mgkg dose which was really found influential against inflammation. The antipyretic activity was evaluated by brewers yeastinduced fever models in.
Antipyretic activity of methanolic stem bark extracts of h. The plant contains terpenoids, alkaloids, flavonoids, and is traditionally known as an aphrodisiac, renal tonic, and for its healthpromoting properties. The antiinflammatory activity of the various extracts was studied based on their effects on carrageenaninduced paw oedema in rats while antipyretic activity was evaluated on the basis of their effect on brewers yeastinduced pyrexia in rats. Preliminary phytochemical and pharmacognostical screening. Analgesic, antiinflammatory and antipyretic activities of.
Analgesics, antipyretics, nonsteroidal antiinflammatory drugs, drugs used to treat gout, and. It is described in ayurvedic literature as ikshura, ikshugandha, and kokilasha having eyes like the kokila or indian cuckoo. This would be useful in its subsequent development for clinical application. Antipyretics cause the hypothalamus to ignore increases in temperature caused by prostaglandin.
In the acute toxicity study, no mortality occurred. D, thesis 20 integral university 62 minerals choudhary and bandyopadhyay 1998 identified the presence of high concentration of fe, cu, and co in all organs of h, spinosa. Antipyretic activity of some nigerian medicinal plants in. Studies of the antiinflammatory and antipyretic activities of the methanolic extract of piper sarmentosum roxb. Although the leaves of the plant is used traditionally in the treatment of pyrexia and its antipyretic related activities such as. These activities are essential in the symptomatic treatment of malaria fever, thereby justifying the folk use ofnefang.
Antinociceptive, antiinflammatory, and antipyretic activity. Antipyretic activity antipyretic activity of drug was measured by slightly modifying the method described by adams et al. Acetylsalicylic acid the principal effects of acetylsalicylic acid are antiinflammatory, analgesic, antipyretic and antiplatelet. The plant contains terpenoids, alkaloids, flavonoids. The assessment of antipyretic activity was carried out using brewers yeast induced pyrexia in wistar rats 8. The antipyretic activity exhibited that the both petroleum ether and chloroform fraction of ethanol extract of roots possess a significant antipyretic effect in maintaining normal body temperature and reducing boiled milk induced elevated rectal temperature in rabbits and their effect are comparable to that of standard antipyretic drug aspirin.
Based on this fact as well as in view of the diversified activities reported from the genus gymnosporia, the present study was designed to evaluate the antipyretic and antiinflammatory activity of gymnosporia royleana g royleana. Antipyretic and antinociceptive activity of diospyros. Antipyretic activity of medicinal plants of cholistan. Plant extracts were prepared by soaking air dried and milled plant material in ethanol for one week, followed by filtration and evaporation at 35oc. Antipyretic and analgesic effects of the aqueous extract.
Antipyretic effect of petroleum ether and chloroform soluble fractions of ethanol extract of the roots of vernonia cinerea was investigated. Fever is a complex physiological response triggered by infectious or aseptic stimuli. Antipyretic activity of orally administered extracts of. In general, nonsteroidal antiinflammatory drugs produce their antipyretic action through the inhibition of prostaglandin synthetase within the hypothalamus 19. The lesson to be learned from this master teacher, baruch spinoza, is that. Comparative antipyretic activity of ethanolic extracts of some species of cynodon in rabbits. Improvement of the understanding, ethics and correspondence. A decrease in temperature can be achieved by administration of compounds with antipyretic activity. Antipyretic activity of ijpcr, octoberdecember 2012, vol 4, issue 4, 4851 page 49 toxic to the hepatic cells, glomeruli, cortex of the brain and heart muscle. In india it is commonly known as kokilaksha or gokulakanta, in sri lanka as neeramulli.
Antinociceptive and antipyretic activities from dracaena loureiri reanmongkol, w. Anders acanthaceae is commonly used in the traditional system of medicine for the treatment of inflammation, pain, jaundice, rheumatism, arthritis, anaemia, etc. The noblest and most lovable of the great philosophers. The normal body temperature of each animal was measured by digital telethermometer and recorded. In the present study, we investigated the antiinflammatory and antipyretic activities of the petroleum ether, chloroform, alcoholic and aqueous. Analgesic and antipyretic activities of the methanolic. Some of the reports coincide for a given species, and, therefore, a total of 17. Nonopioid analgesics with little or no antiinflammatory activity include paracetamol. Pharmacological evidence for the folk use of nefang. In the present study, we investigated the antiinflammatory and antipyretic activities of the petroleum ether, chloroform, alcoholic and aqueous extracts of the leaf of this plant. Based on this fact as well as in view of the diversified activities reported from the genus gymnosporia, the present study was designed to evaluate the antipyretic and antiinflammatory activity of. An ant ipyretic activity is regarded as a positive side effect.
The study aims to evaluate analgesic and antipyretic activities of the methanol extract and its different fractions from root of schoenoplectus grossus using acetic acid induced writhing and radiant heat tail flick method of pain models in mice and yeast induced pyrexia in rats at the doses of 400 and 200 mgkg. The present investigation was carried out to study the antipyretic activity of polyalthia longifolia extracts in wistar rats against lipopolysaccharide lps induced pyrexia. Oral doses are absorbed rapidly from the gastrointestinal. Studies on antiinflammatory, antipyretic and analgesic. Medicinal properties demulcent aphrodisiac diuretic urinary tonic hepatoprotective medicinal parts aerial parts root has medicinal uses yes do not selfadminister no do no use if pregnant no legally restricted no toxicity precautions medicinal notes hygrophila spinosa has too many possible beneficial herbal uses to fully enumerate. Spinozas magnum opus, the ethics, was published posthumously in the year of his death. Therefore, in the present study, we investigated the effects of c. Antipyretic activity of chloroform extracts of geniosporum. Evaluation of analgesic and antipyretic activity of marsilea trifolia blanco. It is considered the best drug in terms of availability, economy, ease of administration, etc. Intraperitoneal administration of boiled milk at a dose 0.
1415 178 543 88 700 521 185 1341 1380 738 1350 468 326 834 588 621 709 462 515 823 601 696 22 212 1337 1466 396 1216 55 827 805 1240 157 301 1285 1166 964 453 904 1089 782 1275 57 996